Regulation of adipocyte lipolysis

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Regulation of adipocyte lipolysis.

In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting conditions or times of elevated energy demands is tightly regulated by neuroendocrine signals, resulting in the activation of lipolytic enzymes. Among the classic regulators of lipolysis, adrenergic stimulation and the insulin-mediated control of lipid mobilisation are the best known. Initially, hormone-sensit...

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Regulation of forearm lipolysis in different types of obesity. In vivo evidence for adipocyte heterogeneity.

UNLABELLED Forearm and systemic adipose tissue free fatty acid (FFA) release was measured in eight nonobese, six lower-body obese, and eight upper-body obese women under basal, hyperinsulinemic, and hypoinsulinemic conditions to determine whether forearm fat is regulated in a similar manner as whole body fat. RESULTS Adipose tissue palmitate release was greater from forearm than whole body (5...

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The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis.

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ژورنال

عنوان ژورنال: Nutrition Research Reviews

سال: 2014

ISSN: 0954-4224,1475-2700

DOI: 10.1017/s095442241400002x